Sven Wach Selected Research

ethylamine

2/2017	A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.
10/2015	The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines.

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Sven Wach Research Topics

Disease

53	Neoplasms (Cancer) 04/2022 - 04/2010
20	Prostatic Neoplasms (Prostate Cancer) 05/2022 - 04/2010
19	Carcinoma (Carcinomatosis) 01/2022 - 04/2010
16	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 01/2013
16	Renal Cell Carcinoma (Grawitz Tumor) 01/2022 - 06/2015
8	Non-Muscle Invasive Bladder Neoplasms 01/2022 - 11/2016
6	Neoplasm Metastasis (Metastasis) 11/2020 - 01/2016
5	Carcinogenesis 11/2020 - 01/2012
4	Lymphatic Metastasis 10/2019 - 07/2013
3	Hypoxia (Hypoxemia) 08/2020 - 06/2015
2	Inflammation (Inflammations) 01/2022 - 09/2015
2	Urologic Neoplasms (Urological Cancer) 01/2022 - 10/2015
2	Breast Neoplasms (Breast Cancer) 09/2020 - 01/2018
2	Leukemia 01/2019 - 10/2015
1	Pathologic Constriction (Stenosis) 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 01/2022
1	Circulating Neoplastic Cells 11/2021
1	Microsatellite Instability 09/2021
1	Melanoma (Melanoma, Malignant) 11/2020
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2019
1	Genetic Translocation (Chromosomal Translocation) 01/2019
1	Heart Failure 11/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2017

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 05/2022 - 11/2010
16	Biomarkers (Surrogate Marker)IBA 05/2022 - 02/2012
16	MicroRNAs (MicroRNA)IBA 11/2020 - 04/2010
13	Messenger RNA (mRNA)IBA 01/2022 - 04/2010
6	Phenobarbital (Luminal)FDA Link 11/2021 - 11/2016
5	HLA-G Antigens (HLA G)IBA 01/2022 - 06/2015
5	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 06/2015
4	Androgen Receptors (Androgen Receptor)IBA 06/2021 - 06/2017
4	ParaffinIBA 01/2016 - 07/2013
3	ProgranulinsIBA 05/2022 - 01/2018
3	RNA (Ribonucleic Acid)IBA 08/2020 - 01/2014
3	DigitoxigeninIBA 11/2018 - 10/2015
3	3- (2- (1- amantadine)- 1- one- ethylamine)digitoxigeninIBA 11/2018 - 10/2015
3	CardenolidesIBA 11/2018 - 10/2015
3	Formaldehyde (Formol)FDA Link 01/2016 - 07/2013
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 10/2016
2	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2020 - 01/2020
2	Urokinase Plasminogen Activator ReceptorsIBA 06/2019 - 09/2015
2	NucleotidesIBA 01/2019 - 01/2012
2	Cadherins (E-Cadherin)IBA 01/2019 - 07/2013
2	SurvivinIBA 11/2018 - 06/2015
2	Cardiac GlycosidesIBA 11/2018 - 02/2017
2	Docetaxel (Taxotere)FDA Link 11/2018 - 06/2016
2	Amantadine (Aman)FDA LinkGeneric 02/2017 - 10/2015
2	Digitoxin FDA Link 02/2017 - 10/2015
2	ethylamineIBA 02/2017 - 10/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2015 - 02/2013
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2022
1	Estrogen Receptor alphaIBA 01/2022
1	serum P-component (CIt)IBA 01/2022
1	CreatinineIBA 01/2022
1	Cell-Free Nucleic AcidsIBA 11/2021
1	Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA 01/2021
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2021
1	CC ChemokinesIBA 01/2021
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2021
1	LigandsIBA 01/2021
1	Programmed Cell Death 1 ReceptorIBA 01/2020
1	B7-H1 AntigenIBA 01/2020
1	Biological ProductsIBA 01/2020
1	PlatinumIBA 01/2020
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 12/2019
1	intrinsic factor-cobalamin receptorIBA 12/2019
1	C-Reactive ProteinIBA 11/2019
1	GP 4 (GP4)IBA 10/2019
1	3' Untranslated Regions (3' UTR)IBA 06/2019
1	LuciferasesIBA 06/2019
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2019
1	pembrolizumabIBA 01/2019
1	Circulating Tumor DNAIBA 01/2019
1	atezolizumabIBA 01/2019
1	Hematoxylin (Haematoxylon)IBA 01/2019
1	Tumor Biomarkers (Tumor Markers)IBA 01/2019
1	Hormones (Hormone)IBA 11/2018
1	AndrogensIBA 11/2018
1	Cyclin B1IBA 11/2018
1	Adenosine Triphosphatases (ATPase)IBA 11/2018
1	PotassiumIBA 03/2018
1	Trace Elements (Biometals)IBA 03/2018
1	ElementsIBA 03/2018
1	CalciumIBA 03/2018
1	StrontiumIBA 03/2018
1	HLA-A Antigens (HLA-A)IBA 05/2017
1	HLA-DR Antigens (HLA-DR)IBA 05/2017

Therapy/Procedure

16	Therapeutics 05/2022 - 10/2015
11	Cystectomy 01/2022 - 07/2011
7	Drug Therapy (Chemotherapy) 01/2021 - 02/2013
5	Adjuvant Chemotherapy 01/2021 - 07/2011
2	Kidney Transplantation 01/2022 - 01/2013
2	Immunotherapy 01/2020 - 01/2020
2	Nephroureterectomy 01/2017 - 07/2015
1	Transurethral Resection of Bladder 04/2022
1	Transplantation 01/2022
1	Prostatectomy (Retropubic Prostatectomy) 01/2022
1	Aftercare (After-Treatment) 01/2020
1	Chemoradiotherapy 01/2017